Hepatic expression of genes regulating lipid metabolism in rabbits.

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Daily Rhythms in Expression of Genes of Hepatic Lipid Metabolism in Atlantic Salmon (Salmo salar L.)

In mammals, several genes involved in liver lipid and cholesterol homeostasis are rhythmically expressed with expression shown to be regulated by clock genes via Rev-erb 1α. In order to elucidate clock gene regulation of genes involved in lipid metabolism in Atlantic salmon (Salmo salar L.), the orphan nuclear receptor Rev-erb 1α was cloned and 24 h expression of clock genes, transcription fact...

متن کامل

Expression profiling of hepatic genes associated with lipid metabolism in nephrotic rats.

Hyperlipidemia is one of the major features of nephrotic syndrome (NS). Although many factors have been implicated in the pathogenesis of NS-related dyslipidemia, the underlying mechanisms remain largely uncharacterized. The present study was designed to examine the gene profile associated with lipid metabolism in the livers of nephrotic rats. NS was created in male Sprague-Dawley rats (n = 6) ...

متن کامل

Adiponectin regulates expression of hepatic genes critical for glucose and lipid metabolism.

The effects of adiponectin on hepatic glucose and lipid metabolism at transcriptional level are largely unknown. We profiled hepatic gene expression in adiponectin knockout (KO) and wild-type (WT) mice by RNA sequencing. Compared with WT mice, adiponectin KO mice fed a chow diet exhibited decreased mRNA expression of rate-limiting enzymes in several important glucose and lipid metabolic pathway...

متن کامل

MicroRNAs regulating lipid metabolism in atherogenesis.

MicroRNAs have emerged as important post-transcriptional regulators of lipid metabolism, and represent a new class of targets for therapeutic intervention. Recently, microRNA-33a and b (miR-33a/b) were discovered as key regulators of metabolic programs including cholesterol and fatty acid homeostasis. These intronic microRNAs are embedded in the sterol response element binding protein genes, S...

متن کامل

SIRT7 and hepatic lipid metabolism

The mammalian sirtuin family, consisting of NAD+-dependent class III histone/protein deacetylases, has 7 members (Greiss and Gartner, 2009). The physiological activities and pathological associations of sirtuins have been subjects of intense interest, as these are key regulators of metabolic processes that often impinge on health, aging and lifespan (Chalkiadaki and Guarente, 2012; Houtkooper e...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Lipid Research

سال: 1993

ISSN: 0022-2275

DOI: 10.1016/s0022-2275(20)35108-7